| 摘要 |
Certain derivatives of oxophthalazinyl acetic acids of the formula <CHEM> wherein R1 is hydroxy or a prodrug group, and R2 and R3 are independently hydrogen, fluoro, chloro or trifluoromethyl, except that R2 and R3 are not both hydrogen, or a pharmaceutically acceptable base addition salt of a compound of formula I wherein R1 is hydroxy, are capable of lowering blood uric acid levels in mammals. These oxophthalazinyl acetic acid derivatives are for instance useful for treating gout and gouty arthritis in a mammal. |
