发明名称 |
SCATTERED TOTAL INTERNAL REFLECTANCE APPARATUS |
摘要 |
A new immunoassay system is provided for the detection of ligands or ligand binding partners in solution in a heterogeneous format. The invention relies upon the detection of back scattered light from an evanescent wave disturbed by the presence of a colloidal gold label brought to the interface by an immunological reaction. The evanescent wave existing at the interface in turn is the result of a totally internally reflected incident light wave. Placement of the detector at a back angle above the critical angle insures a superior signal-to-noise ratio. Apparatus and methods for scanning, detecting and manipulating light including a scattered total internal reflectance immunoassay system are provided. |
申请公布号 |
GR1000982(B) |
申请公布日期 |
1993.03.31 |
申请号 |
GR19900100571 |
申请日期 |
1990.07.25 |
申请人 |
ORTHO DIAGNOSTIC SYSTEMS INC. |
发明人 |
GREENWOOD L. DAVID;SCHUTT G. ERNEST;UTBERG KARIN |
分类号 |
G01N33/543;A61B6/08;G01J1/04;G01J3/02;G01N21/21;G01N21/47;G01N21/55;G01N33/553;G01N33/58;G02B17/06;G02B27/20 |
主分类号 |
G01N33/543 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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