Assay for gene deletion of GST-1 in human samples based on the polymerase chain reaction

摘要

Methods for the detection of GST-1 gene deletion in human blood or tissue samples. The polymerase chain reaction is used to identify the presence or absence of the GST-1 gene in human clinical samples as a means of assessing susceptibility to neoplasia or toxicity upon chemical exposure. The method may also be used on human tumor samples to assess the possibility of resistance to certain chemotherapeutic agents.