发明名称 N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents
摘要 Novel compounds of the formula below wherein W is azetidine, pyrrolidine or piperidine, Q is a straight chain hydrocarbon radical of 1-4 carbons and may contain a double bond, and <IMAGE> Ar is phenyl, pyridinyl or pyrimidinyl, a process for their preparation, and novel intermediates are disclosed. The novel compounds and the pharmaceutical compositions of this invention are useful in the treatment of hypertension, arrhythmias and angina.
申请公布号 US5198449(A) 申请公布日期 1993.03.30
申请号 US19900515620 申请日期 1990.04.27
申请人 A. H. ROBINS COMPANY INCORPORATED 发明人 SHANKLIN, JR., JAMES R.
分类号 C07D211/28;C07D401/04;C07D401/06;C07D401/12;C07D513/04 主分类号 C07D211/28
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