发明名称 |
THROMBOLYTIC PROTEIN |
摘要 |
PURPOSE:To provide a new thrombolytic protein having high thrombus specificity and exhibiting an anti-coagulative action. CONSTITUTION:The thrombolytic protein of this invention is a hybridized product produced by combining a tissue plasminogen-activator or its modified product with a part or all of the epithelial cell-multiplying factor-like domain of throbomodulin directly or through a linker, and is produced by a genetic recombination method. |
申请公布号 |
JPH0578397(A) |
申请公布日期 |
1993.03.30 |
申请号 |
JP19910029624 |
申请日期 |
1991.01.29 |
申请人 |
SUMITOMO PHARMACEUT CO LTD |
发明人 |
YAMAZAKI CHIE;TAKASU NAOKO;NEGORO TAKAATSU;AGUI HIDEO |
分类号 |
A61K38/22;A61K38/46;A61P7/02;C07K19/00;C12N1/19;C12N1/21;C12N5/10;C12N9/64;C12N15/09;C12N15/58;C12N15/62;C12N15/70;C12N15/81;C12N15/85;C12P21/02;C12R1/19 |
主分类号 |
A61K38/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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