MONOCLONAL ANTIBODIES AGAINST HUMAN CARCINOEMBRYONIC ANTIGEN, PROCESSES FOR THEIR PRODUCTION AND THEIR USE

摘要

4-168271+/MCH Novel antibodies of the disclosure The invention concerns novel monoclonal antibodies with high specificity to and affinity for human carcinoembryonic antigen (CEA), derivatives thereof, processes for the preparation of these antibodies and their derivatives, hybridoma cell lines secreting the antibodies, and processes for the preparation of said cell lines. The monoclonal antibodies of the invention and their derivatives are useful in the diagnosis and therapy of cancer and serial monitoring of cancer patients for recurrent disease or response to therapy. Test kits and pharmaceutical compositions containing said monoclonal anti-CEA antibodies are also subject of the invention.