摘要 |
The present invention provides novel substituted anthraquinones having the formula <IMAGE> wherein R1 and R2 are independently H, alkyl, aryl, or arylalkyl; m and n are independently 1, 2, or 3; X is H, OH, NR3R4, Cl, Br, I, F, alkyl, aryl alkoxy, aroxy, COOR5, or CONR6R7; R3, R4, R5, R6, and R7 are independently H, lower alkyl or aryl useful for inhibiting protein kinase C and treating conditions related to, or affected by inhibition of protein kinase C, particularly cancer tumors, inflammatory disease, reperfusion injury, and cardiac dysfunctions related to reperfusion injury. |