| 摘要 |
PURPOSE:To produce the subject compound suitable for an intermediate for synthesis of a coating material, etc., in a high yield without coloration or reduction of quality by reacting benzyl chloride with acetylacetone in the presence of a base in a solvent such as dimethyl sulfoxide or dimethylacetamide. CONSTITUTION:In production of 3-benzylacetylacetone by reacting benzyl chloride with acetylacetone in the presence of a base in a solvent such as dimethyl sulfoxide or dimethylacetamide, acetyl acetone, the solvent such as dimethyl sulfoxide or dimethylacetamide and the base such as calcium carbide are charged into a reaction vessel at room temperatures and benzyl chloride is subsequently added dropwise with stirring at 80-120 deg.C while allowing 30min. After completion of dropping, the resultant mixture is reacted at 80-120 deg.C for 1hr, thus obtaining the objective 3-benzylacetylacetone in 100% conversion, 81% selectivity and 81% yield. |
