BIOASSAY METHOD

摘要

A bioassay method comprises passing test reagents into the circulation of an embryo in such manner that the reagents are not modified by any intermediate metabolism. This can be effected in e.g. rat embryos by microcannulation directly into the vitelline circulation by passing the visceral yolk sac. In chick embryos the test reagent can be administered directly into the extra-embryonic circulation. The embryo is cultured and assessed as to its embryonic development.