摘要 |
<p>A pyrazolotriazole derivative represented by general formula (I), useful for treating various diseases caused by the physiological activity of angiotensin II, or a pharmaceutically acceptable salt thereof, and a process for the production thereof wherein one of R?1, R3 and R4¿ represents hydrogen, tetrazolylated biphenylmethyl or lower alkyl, and each of the remaining two represents hydrogen, R2 represents hydrogen, tetrazolylated biphenylmethyl, cycloalkyl or lower alkyl, and R?5 and R6¿ may be the same or different from each other and each represents hydrogen, halogen, tetrazolylated biphenylmethyl, formyl, carboxyl, esterified carboxyl, cycloalkyl, lower alkoxy, lower alkoxycarbonyl, or lower alkyl, provided that at least one of R1 to R6 is tetrazolylated biphenylmethyl and the broken lines mean that the triazole ring forms three double bonds.</p> |