The present invention relates to a new assay system which can be used to screen for and to quantitate infectious retroviral strains. In particular, the present invention relates to a simple and rapid colorimetric transactivation assay for the detection of HIV-1, HIV-2 and SIV using HeLa cells containing CD4 and a reporter gene, for example beta -galactosidase, that is dependent on transactivation by the infecting virus for expression.
申请公布号
WO9305185(A1)
申请公布日期
1993.03.18
申请号
WO1992US07386
申请日期
1992.09.08
申请人
THE UNITED STATES OF AMERICA, REPRESENTED BY THE S
发明人
REITZ, MARVIN, S.;WATERS, DAVID, J.;BLATTNER, WILLIAM;WILSON, CAROLYN, A.
