发明名称 |
PEPTIDE INHIBITORS OF INFLAMMATION MEDIATED BY SELECTINS |
摘要 |
2118695 9305070 PCTABS00020 Peptides derived from three regions of the lectin domain of GMP-140 and the related selectins, ELAM-1 and the lymphocyte homing receptor, have been found to inhibit neutrophil adhesion to GMP-140. The peptides are useful as diagnostics and, in combination with a suitable pharmaceutical carrier, for clinical applications in the modulation or inhibition of coagulation processes or inflammatory processes.
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申请公布号 |
CA2118695(A1) |
申请公布日期 |
1993.03.18 |
申请号 |
CA19922118695 |
申请日期 |
1992.09.09 |
申请人 |
CENTOCOR INC;UNIV OKLAHOMA STATE;UNIV OKLAHOMA STATE |
发明人 |
HEAVNER GEORGE A;MCEVER RODGER P;GENG JIAN-GUO |
分类号 |
C12N15/09;A61K38/00;A61P7/02;A61P29/00;C07K7/06;C07K7/08;C07K14/705;C07K14/78;C12P21/02;(IPC1-7):C12N15/12;A61K38/04;A61K38/17;G01N33/554;G01N33/566 |
主分类号 |
C12N15/09 |
代理机构 |
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地址 |
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