发明名称 5-HT4 RECEPTOR ANTAGONISTS
摘要 2118812 9305038 PCTABS00020 The use of a compound of formula (I) or pharmaceutically acceptable salt thereof, in which X1-(CH2)x-X2 forms a 5-7 membered ring wherein: X1 is O or S; X2 is O, S, NR or NRCO wherein R is hydrogen or C1-6alkyl; x is 1, 2 or 3; Y is O or NH; Z is sub-formula (a), (b) or (c) in the manufacture of a medicament for use in the treatment of gastrointestinal disorders, cardiovascular disorders and CNS disorders.
申请公布号 CA2118812(A1) 申请公布日期 1993.03.18
申请号 CA19922118812 申请日期 1992.09.09
申请人 SMITHKLINE BEECHAM PLC 发明人 KING FRANCIS D;GASTER LARAMIE M;MULHOLLAND KEITH R;RAHMAN SHIRLEY K;WYMAN PAUL A;SANGER GARETH J;WARDLE KAY A;BAXTER GORDON S;KENNETT GUY A;KAUMAN ALBERTO J
分类号 A61K31/245;A61K31/38;A61K31/395;A61K31/40;A61K31/415;A61K31/435;A61K31/437;A61K31/44;A61K31/4427;A61K31/443;A61K31/445;A61K31/4453;A61K31/452;A61K31/454;A61K31/47;A61K31/535;A61K31/55;A61P9/06;A61P25/00;A61P25/20;A61P43/00;C07D209/42;C07D401/12;C07D405/12;C07D409/12;C07D413/04;C07D413/12;C07D413/14;C07D455/02;C07D471/04;(IPC1-7):C07D471/04;C07D411/12;C07D417/12;C07D319/18;A61K31/442 主分类号 A61K31/245
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