摘要 |
<p>The present invention provides a fermentative process for producing riboflavin. In this process, a mutant which belongs to the genus Bacillus, is lowered in the activity of liberating phosphoric acid from 5'-guanylic acid and has the ability of producing riboflavin is cultured in a liquid medium to produce/accumulate riboflavin. Mutants used in the process of this invention have an improved ability of producing riboflavin and are capable of producing/accumulating a markedly increased amount of riboflavin in the culture medium, compared with the parent strain. The process of this invention is therefore suited as a process for producing riboflavin in an effective manner at a low cost.</p> |