| 发明名称 |
MUTEINS OF EPIDERMAL GROWTH FACTOR EXHIBITING ENHANCED BINDING AT LOW PH |
| 摘要 |
EGF muteins in which the histidine at position 16 is replaced with a neutral or acidic amino acid exhibit activity at pHs lower than obtainable with wild type EGF. |
| 申请公布号 |
AU2489992(A) |
申请公布日期 |
1993.03.16 |
| 申请号 |
AU19920024899 |
申请日期 |
1992.08.14 |
| 申请人 |
CHIRON CORPORATION |
发明人 |
GUY T MULLENBACH;JEFFREY M BLANEY;STEVEN ROSENBERG |
| 分类号 |
A61K38/00;C07K14/485;C12N15/18 |
主分类号 |
A61K38/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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