| 摘要 |
Fecal occult blood tests of enhanced sensitivity, specificity, and readability are provided by employing a developer or complete reagent solution that uses as a solvent system a solvent comprising at least about 50% by volume of a solvent for iron protoporphyrins. In a preferred embodiment, the solvent for iron protoporphyrins comprises a mixture of a neutralized amine and an organic co-solvent. Alternatively, the solvent may comprise pyridine, an amide, a sulfoxide or sulfone, or mixtures thereof. Test results may be improved by incorporating hemoprotein solubilizing agents, plant peroxidase inhibitors, iron/copper chelating agents, accelerators and buffers in the developer/reagent.
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