摘要 |
A device for simultaneous collection of cells from the endocervical canal and the cervical face of the uterus and methods of use. The device is an elongated handle having one cell-collecting member projecting from the handle at an axis perpendicular to the axis of the handle for contacting with the cervical face of the uterus, and one cell-collecting member projecting from the handle along the same axis as the handle for contacting with the endocervical canal of the uterus. Along each member project sets of bristles which, because they are perpendicularly positioned on each member, provide mild abrasive action to the endocervical canal and the cervical face when the device is inserted into the uterus and rotated, so that cells from both regions are collected onto the bristles. The cells are removed from the bristles either by bending a flexible portion of the handle to enable parallel smearing of the cells onto a microscope slide, or by dislodging the cells from the bristles of the device into a fixative solution by manually rotating the device. After the solution is centrifuged, the cells form a cell pellet which is then smeared onto a microscope slide as a single layer of cells.
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