发明名称 |
USE OF A PROSTAGLANDIN IN COMBINATION WITH AN ADRENERGIC BLOCKING AGENT FOR REDUCTION OF INTRAOCULAR PRESSURE |
摘要 |
USE OF A PROSTAGLANDIN IN COMBINATION WITH AN ADRENERGIC BLOCKING AGENT FOR REDUCTION OF INTRAOCULAR PRESSURE of The Disclosure This invention provides a method for treating ocular hypertension or glaucoma in a subject's eye. The method comprises contacting the surface of the eye with an effective intraocular pressure reducing amount of a mixture of an adrenergic blocking agent and a prostaglandin or prostaglandin derivative in an ophthalmically compatible carrier, so as to reduce the intraocular pressure of the eye and maintain such reduced intraocular pressure. This invention also provides a composition for topical treatment of ocular hypertension or glaucoma in the eye of a subject. The composition comprises an effective intraocular pressure reducing amount of a mixture of an adrenergic blocking agent and a prostaglandin or prostaglandin derivative in an ophthalmically compatible carrier.
|
申请公布号 |
CA1314220(C) |
申请公布日期 |
1993.03.09 |
申请号 |
CA19880562902 |
申请日期 |
1988.03.30 |
申请人 |
TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (THE);KABI PHARMACIA AB |
发明人 |
BITO, LASZLO Z.;STJERNSCHANTZ, JOHAN W. |
分类号 |
A61K31/41;A61K31/135;A61K31/535;A61K31/557;A61P27/02;A61P27/06;(IPC1-7):A61K31/557 |
主分类号 |
A61K31/41 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|