发明名称 USE OF A PROSTAGLANDIN IN COMBINATION WITH AN ADRENERGIC BLOCKING AGENT FOR REDUCTION OF INTRAOCULAR PRESSURE
摘要 USE OF A PROSTAGLANDIN IN COMBINATION WITH AN ADRENERGIC BLOCKING AGENT FOR REDUCTION OF INTRAOCULAR PRESSURE of The Disclosure This invention provides a method for treating ocular hypertension or glaucoma in a subject's eye. The method comprises contacting the surface of the eye with an effective intraocular pressure reducing amount of a mixture of an adrenergic blocking agent and a prostaglandin or prostaglandin derivative in an ophthalmically compatible carrier, so as to reduce the intraocular pressure of the eye and maintain such reduced intraocular pressure. This invention also provides a composition for topical treatment of ocular hypertension or glaucoma in the eye of a subject. The composition comprises an effective intraocular pressure reducing amount of a mixture of an adrenergic blocking agent and a prostaglandin or prostaglandin derivative in an ophthalmically compatible carrier.
申请公布号 CA1314220(C) 申请公布日期 1993.03.09
申请号 CA19880562902 申请日期 1988.03.30
申请人 TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (THE);KABI PHARMACIA AB 发明人 BITO, LASZLO Z.;STJERNSCHANTZ, JOHAN W.
分类号 A61K31/41;A61K31/135;A61K31/535;A61K31/557;A61P27/02;A61P27/06;(IPC1-7):A61K31/557 主分类号 A61K31/41
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