发明名称 |
HEPATITIS C ASSAY UTILIZING RECOMBINANT ANTIGENS TO NS1 |
摘要 |
The present invention provides unique recombinant antigens representing distinct antigenic regions of the NS1 region of the HCV genome which can be used as reagents for the detection of antibodies and antigen in body fluids from individuals exposed to hepatitis C virus (HCV). The present invention also provides an assay for detecting the presence of an antibody to an HCV antigen in a sample by contacting the sample with the recombinant antigens. Preferred assay formats include a screening assay, a confirmatory assay, a competition or neutralization assay and an immunodot assay. |
申请公布号 |
WO9304088(A1) |
申请公布日期 |
1993.03.04 |
申请号 |
WO1992US07188 |
申请日期 |
1992.08.21 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
DAILEY, STEPHEN, H.;DESAI, SURESH, M.;DEVARE, SUSHIL, G. |
分类号 |
C07K14/00;C07K14/02;C07K14/10;C07K14/18;C07K19/00;C12N9/12;C12N15/09;C12R1/19;G01N33/53;G01N33/576 |
主分类号 |
C07K14/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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