HIV-TREATMENT METHOD WITH LOW-TOXICITY AMPHOTERICIN B

摘要

A method of inhibiting HIV infection in peripheral blood macrophages, as evidenced by an inhibition of HIV p24 antigen expression in the infected cells. The method includes exposing the infected macrophages to a composition containing particles of amphotericin B:cholesteryl sulfate, molar ratio 1:0.5 to 1:4, at a concentration of at least about 0.01 mu M amphotericin B.