发明名称 |
METHODS AND COMPOSITIONS FOR MODULATING G PROTEIN ACTION |
摘要 |
The present disclosure relates to methods and compositions for modulating the action of G proteins. G proteins are important to cellular regulation in all human cells and their function is involved in a wide variety of human disease processes. In particular aspects, the present disclosure concerns the development of mastoparan analogs as well as other amphipathic and cationic peptides, termed receptor-based analogues, that can promote activation of one or more G proteins, and are therefore proposed to be useful in the treatment of a variety of disorders including asthma, ulcers, cardiovascular diseases and even Parkinson's disease. |
申请公布号 |
WO9303749(A1) |
申请公布日期 |
1993.03.04 |
申请号 |
WO1992US06825 |
申请日期 |
1992.08.14 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
HIGASHIJIMA, TSUTOMU;ROSS, ELLIOTT, M. |
分类号 |
A61K38/00;C07K14/435 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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