发明名称 |
RECEPTORS FOR ADVANCED GLYCOSYLATION ENDPRODUCTS AND USES THEREOF |
摘要 |
The present invention relates to a receptor for advanced glycosylation endproducts that may be derived from rat liver membranes or mesangial cells, and that specifically comprises certain proteins determined to possess molecular masses of about 90 kD, 60 kD, 50 kD, 40 kD and 30-35 kD, respectively, as assessed by migration during SDS-PAGE. Partial N-terminal sequences have been determined and diagnostic and therapeutic agents, compositions and methods are proposed. |
申请公布号 |
WO9304086(A1) |
申请公布日期 |
1993.03.04 |
申请号 |
WO1992US07155 |
申请日期 |
1992.08.24 |
申请人 |
THE ROCKEFELLER UNIVERSITY |
发明人 |
VLASSARA, HELEN;YANG, ZHI;CERAMI, ANTHONY |
分类号 |
A61K38/00;C07K14/705;C07K16/28;G01N33/573 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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