发明名称 ANTI-TUMOR PLATINUM COMPLEXES
摘要 PCT No. PCT/EP92/01623 Sec. 371 Date Feb. 22, 1994 Sec. 102(e) Date Feb. 22, 1994 PCT Filed Jul. 17, 1992 PCT Pub. No. WO93/03046 PCT Pub. Date Feb. 18, 1993.Compounds of formula (1): (am)2Pt O-CO-C6H4-NH2(p), (Cl)n (HCl)n (ROH)m(1) in which am is a monovalent amine ligand which is NH3, a linear or branched C1-C6 alkylamine, a cyclic amine of 3-6 carbon atoms, or the two am groups form a linear or cyclic C2-8-alkyl-1,2 diamine or 1,3-diamine; R is hydrogen or C1-3 alkyl; n1, and m are independently zero or 1 and n is 1, are active in the treatment of several tumors, including tumor of ovary, breast, lungs, melanoma, microcytoma.
申请公布号 AU2344892(A) 申请公布日期 1993.03.02
申请号 AU19920023448 申请日期 1992.07.17
申请人 ISTITUTO NAZIONALE PER LA RICERCA SUL CANCRO 发明人 MAURO ESPOSITO
分类号 C07F15/00 主分类号 C07F15/00
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