摘要 |
PCT No. PCT/EP92/01623 Sec. 371 Date Feb. 22, 1994 Sec. 102(e) Date Feb. 22, 1994 PCT Filed Jul. 17, 1992 PCT Pub. No. WO93/03046 PCT Pub. Date Feb. 18, 1993.Compounds of formula (1): (am)2Pt O-CO-C6H4-NH2(p), (Cl)n (HCl)n (ROH)m(1) in which am is a monovalent amine ligand which is NH3, a linear or branched C1-C6 alkylamine, a cyclic amine of 3-6 carbon atoms, or the two am groups form a linear or cyclic C2-8-alkyl-1,2 diamine or 1,3-diamine; R is hydrogen or C1-3 alkyl; n1, and m are independently zero or 1 and n is 1, are active in the treatment of several tumors, including tumor of ovary, breast, lungs, melanoma, microcytoma. |