| 发明名称 |
PROCESSO PARA A PREPARACAO DE FACTOR DE ACTIVACAO DOS NEUTROFILOS |
| 摘要 |
Neutrophil-activating factor (NAF) is claimed. More specifically it has the qiven complete amino acid sequence. Also claimed is DNA having the nucleotide sequence indicated and equivalents suitable for expression in E.coli of NAF. - The total amino acid sequence of NAF purified from LPS-stimulated human monocytes has been detd. and a gene coding for the main NAF species synthesised and expressed as a recombinant peptide with the same neutrophil-activating properties as its natural homologue. |
| 申请公布号 |
PT89026(B) |
申请公布日期 |
1993.02.26 |
| 申请号 |
PT19880089026 |
申请日期 |
1988.11.17 |
| 申请人 |
SANDOZ SA.;THEODOR KOCHER INSTITUT |
发明人 |
ALFRED WALZ;HEINRICH ASCHAUER;IVAN JAMES DALDON LINDLEY;PAOLA PEVERI |
| 分类号 |
C12N1/21;A47L5/36;A47L9/00;A61K38/00;A61P11/00;A61P17/00;A61P29/00;A61P31/00;A61P31/04;A61P31/12;C07H21/04;C07K1/16;C07K1/20;C07K1/22;C07K14/47;C07K14/52;C07K14/53;C07K14/54;C12N1/14;C12N1/20;C12N5/00;C12N15/00;C12N15/09;C12N15/12;C12N15/19;C12N15/70;C12P19/34;C12P21/02;C12R1/19;C12R1/91 |
主分类号 |
C12N1/21 |
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