发明名称 TETRAHYDROTIOFENDERIVAT
摘要 <p>A compound of the formula [I] and pharmaceutically acceptable salts thereof; and a synthetic intermediate represented by the fomula [II] and pharmaceutically acceptable salts thereof, <CHEM> <CHEM> wherein R 1 is hydrogen or lower alkyl; R 2 is hydrogen or a protective group of thiol; R 3 is hydroxy, a remainder of ester group or a remainder of amido group; A is straight or branched lower alkylene, and the sulfur atom in the side chain may be directly join with -CO- to conform a thiolactone ring. The compounds of this invention have excellent thymulin-like activities and are expected to be useful for treatment of various immune disorders such as immunodeficiency and autoimmune diseases.</p>
申请公布号 FI930873(A0) 申请公布日期 1993.02.26
申请号 FI19930000873 申请日期 1993.02.26
申请人 SANTEN PHARMACEUTICAL CO., LTD. 发明人 MITA, SHIRO;KAWASHIMA, YOICHI;KATO, NOBUHARU;SUHARA, HIROSHI;YONEDA, KOJI;MORISHITA, MASATAKA
分类号 A61K31/38;A61K31/381;A61P37/00;A61P37/04;C07D333/38;C07D409/06;C07D409/12;C07D409/14;C07D495/08 主分类号 A61K31/38
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