| 摘要 |
<p>NEW MATERIAL:The titled compound of formula I [X is halogen; R1 is H or aliphatic hydrocarbon residue (the substituent group is selected from carboxy, etc.); R2 is H, lower alkyl, etc.; R3 is carboxy]. EXAMPLE:( + or - )-cis-7-( 4-Bromo-3-oxo-2-methoxyiminobutyrylamino )-1-azabicyclo [4,2,0]oct-2-en-8-one-2-carboxylic acid. USE:Antibacterial agent, disinfectant, etc. PROCESS:The compound of formula I can be prepared by condensing the compound of formula III or its reactive derivative (e.g. acid halide, etc.) with the compound of formula IV, its salt or its equivalent (called generally as 7-amino compounds), and if necessary, eliminating the protecting group of R3 by conventional method, and further converting to a proper salt.</p> |
