SUBSTITUTED 2-HYDROXY-1,3-BIS-AMINES, METHODS OF PREPARING THEM, AND THEIR USE

摘要

Disclosed are compounds of the formula (I), in which R(1) is H alk(en)yl or benzyl; R(2) and R(3) are H, (cyclo)alk(en)yl, phenyl, phenylalkyl, phenylalkenyl or benzhydryl(alkyl) or, together with the N, forms a ring; R(4) is H, (cyclo)alk(en)yl, alkanoyl, hydroxyalkyl, pyridyl, pyrimidinyl, pyrazinyl, phenyl, phenylalk(en)yl, benzhydryl(alkyl) or phenyl(alkanoyl); R(5) and R(6) are H, OH, halogen, (cyclo)alk(en)yl or phenyl(alkyl); R(7) and R(8) are H, (cyclo)alk(en)yl, Y-(cyclo)alk(en)yl, phenyl(alkyl), Y-(alkyl)phenyl, Y-phenyl-Y-phenyl, biphenylyl, etc; R(9) is H, (Y)-alk(en)yl or (Y)-phenyl; Y is O, S, SO or SO2; m and n are 0-4; and Aryl is phenyl or naphthyl. Such compounds are excellent antimycotics, usable for treatment and prophylaxis.