发明名称 |
Using polyazamacrocyclic compounds for intracellular measurement of metal ions using MRS |
摘要 |
The present invention relates to a method of using a polyazamacrocyclic compound or a salt thereof to measure intracellular metal ions formula <IMAGE> where x is 2, 3 or a combination of p 2(s) and q 3(s) where p +q=y; y is 3 or 4; R is (CH2)zP(=O)R1R2; R1 is R3 or OR3 where R3 is alkyl, cycloalkyl or aryl; R2 is H, alkyl or <IMAGE> where R4 is alkyl, cycloalkyl or aryl; and z is 1 to 3.
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申请公布号 |
US5188816(A) |
申请公布日期 |
1993.02.23 |
申请号 |
US19910798599 |
申请日期 |
1991.11.26 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
SHERRY, A. DEAN;LAZAR, ISTVAN;BRUCHER, ERNO;RAMASAMY, RAVICHANDRAN |
分类号 |
A61K49/06;A61K51/04;C07D255/02;C07D257/02;C07F9/6515;C07F9/6524 |
主分类号 |
A61K49/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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