摘要 |
<p>A system and method of achieving both convective and diffusive transport of plasma across a membrane (30) accompanied by the selective removal of plasma components using sorbents (33) followed by reinfusion of the purified plasma in a blood circulation system is achieved by pumping blood through a filter (30) comprising a bundle of ''U'' shaped hollow fibers immersed in a closed plasma chamber (31) containing sorbents (33) in a plasma chamber solution (32). As blood flows through the entry arm (32), due to positive transmembrane pressure difference, plasma filtration into the plasma chamber (31) occurs. However, the transmembrane pressure difference is negative when blood flows out of the exit arm (39) of filter (30) and the direction of filtration reverses causing reverse filtration/reinfusion of plasma from the chamber (31) into the blood in the exit arm (39).</p> |