A method is provided for eliminating cancer cells from a population of cells containing cancer cells and noncancerous cells in vitro or in vivo comprising: (a) providing a mixture of noncancerous cells and cancer cells; (b) contacting the cancer cells with transgenic cancer cells comprising a foreign gene that renders the transgenic cancer cells susceptible to a therapeutic agent; and (c) contacting the transgenic cancer cells with an amount of said therapeutic agent effective to kill both the transgenic cancer cells and the cancer cells.
申请公布号
WO9302556(A1)
申请公布日期
1993.02.18
申请号
WO1992US06188
申请日期
1992.07.24
申请人
UNIVERSITY OF ROCHESTER
发明人
FREEMAN, SCOTT, M.;ABRAHAM, GEORGE, N.;MCCUNE, CRAIG, S.;MOOLTEN, FREDERICK, L.;KOEPLIN, DAVID