发明名称 |
2,4-DICHLOOR-ALFA-(N-IMIDAZOLYLMETHYL)-DIBENZYLETHERDERIVAAT, ALSMEDE EEN DEZE VERBINDING OMVATTEND FARMACEUTISCH PREPARAAT. |
摘要 |
Novel compounds I and their acid addition salts <IMAGE> in which R is phenyl or phenylthio show activity against some fungi, yeasts and gram positive aerobic and anaerobic bacteria. The new compounds can be prepared by condensing 1-(2',4'- dichlorophenyl)-2-(N-imidazolyl- methyl)-ethanol with 4-chloromethyl- biphenyl, 4-bromomethyl-biphenyl, 1- phenylthio-4-chloromethyl-benzene or 1-phenylthio-4-bromomethyl-benzene in a solvent, most preferably dimethylsulphoxide. |
申请公布号 |
NL189255(C) |
申请公布日期 |
1993.02.16 |
申请号 |
NL19790003872 |
申请日期 |
1979.05.16 |
申请人 |
RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY TE CHIASSO, ZWITSERLAND. |
发明人 |
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分类号 |
A61K31/415;A61P31/04;C07C29/143;C07D233/60;C07D521/00;(IPC1-7):C07D233/64 |
主分类号 |
A61K31/415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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