发明名称 Process for the production of stable pharmaceutical dosage forms of an ergoline derivative and pharmaceutical compositions thereby obtained
摘要 The invention relates to novel pharmaceutical compositions intended for ocular administration and to a process for obtaining them. It relates specifically to a process for obtaining pharmaceutical compositions intended for ophthalmic administration in which the active principle is bromocryptine, in which process the active principle is dissolved in methanol and then diluted with an aqueous solution containing a water-soluble inert filler, the mixture is lyophilised and the lyophilisation pellet is then redissolved at the time of use in an aqueous solution containing a preservative, a polyethylene glycol, physiological saline and an ethylenic acid. The solution obtained is a medicament for intraocular hypertension.
申请公布号 FR2680106(A1) 申请公布日期 1993.02.12
申请号 FR19910010159 申请日期 1991.08.09
申请人 CORBIERE GEROME 发明人 CORBIERE JEROME;PETEL JEAN-LUC;BESNARD PHILIPPE
分类号 A61K9/00;A61K31/48 主分类号 A61K9/00
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