MINIATURISIERTER BIOFUEHLER MIT MINIATURISIERTER SAUERSTOFFELEKTRODE SOWIE SEIN HERSTELLUNGSVERFAHREN.

摘要

Miniaturized Clark-type oxygen electrodes comprise a substrate (1) having at least one recess groove formed on a surface thereof for reserving an electrolyte solution, two electrodes (3A, 3B) acting as a cathode and an anode formed through an insulating layer (2) on the surface of the substrate, each of which electrodes is at least partly extended toward a bottom area of the recess, a solid or a semi-solid, porous, electrolyte solution-containing material (4) filling the recess, and an oxygen gas-permeable membrane (5) covering and sealing the recess and porous material reserved therein. Miniaturized biosensors may use the oxygen electrode as a transducer. The oxygen electrodes and biosensors, which are extremely accurate, can be produced on a mass-production scale and can be widely used in various fields such as clinical analysis, industrial processing, and a determination of environmental conditions. The biosensors can be particularly used in clinical diagnosis and monitoring devices for both in vivo and in vitro measurements.