发明名称 Substituted cyclopropylamino-1,3,5-triazines.
摘要 <p>New cyclopropylamino-1,3,5-triazines and their salts, processes for their preparation and therapeutic compositions. These compounds correspond to the formula <IMAGE> in which R1 = alkyl, cycloalkyl or alkylcycloalkyl, R2 = bis(2-hydroxyethyl)amino, 3-hydroxy-1-azetidinyl, 3-methoxy-1-azetidinyl, 3-oxo-1-azetidinyl, morpholino, 4-hydroxypiperidino, thiomorpholino, thiomorpholino S-oxide, thiomorpholino S,S-dioxide, 3-thiazolidinyl, 3-thiazolidinyl S-oxide, 3-thiazolidinyl S,S-dioxide or 8-oxa-3-azabicyclo[3.2.1]oct-3-yl. These compounds are useful in the treatment of disorders associated with Alzheimer's disease, Alzheimer-type senile dementias and all evolutive cognitive pathologies and in the treatment of depression, anxiety, mood disorders, inflammatory phenomena and asthma.</p>
申请公布号 EP0527117(A1) 申请公布日期 1993.02.10
申请号 EP19920870101 申请日期 1992.07.09
申请人 U C B, S.A. 发明人 VAN KEULEN, BEREND JAN;GOLSTEIN, SOLO;COSSEMENT, ERIC;GOBERT, JEAN;WUELFERT, ERNST
分类号 A61K31/53;A61K31/5377;A61K31/541;A61P11/00;A61P11/06;A61P25/20;A61P25/22;A61P25/24;A61P25/26;A61P25/28;A61P29/00;C07D251/12;C07D251/14;C07D251/16;C07D251/18;C07D251/22;C07D401/04;C07D403/04;C07D411/04;C07D413/04;C07D417/04;C07D498/08 主分类号 A61K31/53
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