发明名称 HYDANTOIN DERIVATIVES
摘要 The invention relates to compounds of the formula I in which R1 represents, for example, -(CH2)n-NH-X or -CH2-C6H4-NH- X, wherein n is an integer from 3 to 5 and X represents, for example, hydrogen or C1-C6-alkyl, R2 denotes hydrogen or C1-C6- alkyl, R3 denotes hydrogen or a phenyl radical, R4 denotes, for example, hydrogen and Y denotes, for example, -(CH2)m-CO-, wherein m represents an integer from 1 to 4. The compounds of the invention inhibit platelet aggregation, formation of metastases and binding of osteoclasts to the bone surfaces. They are therefore useful for the prevention of arteriosclerosis, thrombosis and osteoporosis and prophylactically against cancer.
申请公布号 CA2075590(A1) 申请公布日期 1993.02.09
申请号 CA19922075590 申请日期 1992.08.07
申请人 CASSELLA AKTIENGESELLSCHAFT 发明人 KOENIG, WOLFGANG;ZOLLER, GERHARD;JUST, MELITTA;JABLONKA, BERND
分类号 A61K31/415;A61K31/4166;A61K38/00;A61K38/04;A61K38/05;A61K38/06;A61P7/02;A61P9/10;A61P19/10;A61P35/00;A61P43/00;C07D233/76;C07D233/96;C07K1/02;C07K5/02;C07K5/023;C07K5/06;C07K5/062;C07K5/072;C07K5/078;C07K5/08;C07K5/083;C07K5/09;C07K5/097;C07K5/10;C07K5/11;C07K5/117;(IPC1-7):C07K5/023 主分类号 A61K31/415
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