发明名称 3-heteroatom containing urea and thiourea ACAT inhibitors
摘要 Compounds useful in treating hypercholesterolemia and atherosclerosis having the formula <IMAGE> wherein X is oxygen or sulfur, Het is a monocyclic heterocyclic group having three hetero atoms selected from nitrogen, oxygen and sulfur, and R1, R2 and R3 are hydrogen, flourine, chlorine, bromine, a straight or branched alkyl group having from 1 to 6 carbon atoms, a straight or branched alkoxy group having from 1 to 6 carbon atoms, substituted or unsubstituted benzoyl, substituted or unsubstituted benzoyl, substituted or unsubstituted phenyl, amino or substituted amino or a carboxy group.
申请公布号 US5185358(A) 申请公布日期 1993.02.09
申请号 US19910719907 申请日期 1991.06.24
申请人 WARNER-LAMBERT CO. 发明人 CRESWELL, MARK W.;WHITE, ANDREW D.
分类号 A61K31/41;C07D249/12;C07D249/14;C07D271/06;C07D271/07;C07D271/10;C07D271/113;C07D285/12;C07D285/135 主分类号 A61K31/41
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