| 摘要 |
PCT No. PCT/US90/00292 Sec. 371 Date Oct. 23, 1991 Sec. 102(e) Date Oct. 23, 1991 PCT Filed Jan. 16, 1990 PCT Pub. No. US89/02176 PCT Pub. Date May 17, 1989.2-(8-Azabicyclo[3.2.1]oct-8-yl)alkanols of the formula <IMAGE> (I) wherein Q is S or CH=CH; X is H, OH or another aromatic substituent; R is hydrogen, alkyl, alkenyl or alkynyl; Y and Y1 are taken together and are arylmethylene or aralkylmethylene (or a corresponding epoxy derivative) or Y and Y1 are taken separately and Y is hydrogen or OH, and Y1 is aryl, aralkyl, arylthio, or aryloxy; and structurally related 2-(piperidino)alkanols; pharmaceutical compositions thereof; methods of treating CNS disorders therewith; and intermediates useful in the preparation of said compounds.
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