| 摘要 |
Two novel optically pure intermediates, (R)-4-(2-bromo-1-hydroxyethyl)-2-trifluoro(-)methylthiazole and (S)-4-oxiranyl-2-trifluoromethylthiazole, which have utility in the synthesis of a potent class of antidiabetic agents. The invention also embraces an enantioselective reduction process for their preparation. |
