发明名称 METHOD FOR PREPARING PLASMINOGEN ACTIVATORS IN PROCARYOTES
摘要 <p>In order to produce, in a procaryote cell, a plasminogen activator by expressing a c-DNA coding for this activator, which c-DNA is incorporated in a vector that is suitable for the host cell, a strictly controlled vector is used so that its replication cannot be dissociated, or can only be temporarily dissociated from the replication of the chromosome of the host cell. Its culture is carried out in conditions such that no laxity occurs in its control. Plasmids that are particularly suitable for carrying out this process are disclosed.</p>
申请公布号 EP0242835(B1) 申请公布日期 1993.02.03
申请号 EP19870105805 申请日期 1987.04.21
申请人 BOEHRINGER MANNHEIM GMBH 发明人 MATTES, RALF, DR. RER. NAT.
分类号 C12N9/64;C12N9/72;C12N15/00;C12N15/09;C12R1/19;C12R1/40 主分类号 C12N9/64
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