摘要 |
An azole derivative represented by the following formula (I): <IMAGE> (I) wherein X is a nitrogen atom or CH, Y is an oxygen atom, a sulfur atom, an imino group, a methylimino group or a group represented by =N DIFFERENCE O-, Z is one or two halogen atoms, n stands for a number of 1 or 2, the wavy line means that stereochemistry of the double bond is either E or Z; or an acid adduct thereof. They exhibit strong antifungal activities and are very useful in the therapy for fungus diseases. Also disclosed is an antifungal drug containing said compound as an active ingredient.
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