发明名称 METHOD FOR PURIFICATION OF OXIMES
摘要 1. A method for purification of piroxicam, with formula 1, from a raw product, mixed with an adsorbent from the non-organic silicon derivative group, obtained from a high-temperature reaction of ester with general formula 2, wherein R denotes a methyl or an ethyl group, with 2-aminopyridine and its maintenance in the required crystal form with optimum biological availability in oral preparations, characterized in that the raw product is eluted from the solid phase with halogenoalkane at a raised temperature and to the eluate thus obtained lower aliphatic alcohol is added, halogenoalkane is removed through distillation, and piroxicam, crystallized from the alcohol, is isolated and recrystallized by a known method from a dipolar aprotic solvent.<IMAGE>
申请公布号 PL159841(B1) 申请公布日期 1993.01.29
申请号 PL19870269508 申请日期 1987.12.15
申请人 发明人
分类号 C07D;C07D417/12;(IPC1-7):C07D417/12 主分类号 C07D
代理机构 代理人
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