| 摘要 |
<p>A compound of the formula : <CHEM> wherein R<1> is carboxy or protected carboxy, R<2> is hydrogen, lower alkyl or halogen, R<3> is aryl or ar(lower)alkyl, each of which may have suitable substituent(s), [substituted carbamoyl](lower)alkyl, or a group of the formula : <CHEM> in which <CHEM> is heterocyclic group containing nitrogen atom, and n is 0 or 1, R<1><1> is hydrogen or lower alkyl, A is lower alkylene which may be substituted by oxo, or lower alkenylene, Q is carbonyl or lower alkylene, X is <CHEM> in which R<4> is hydrogen or lower alkyl, and R<5> is hydrogen, lower alkyl or Y-Z-R<3>, Y is bond or lower alkylene, Z is lower alkylene, lower alkenylene, -O-or <CHEM> in which R<6> is hydrogen, lower alkyl, ar(lower)alkyl which may have suitable substituent(s) or amino protective group, and pharmaceutically acceptable salts thereof, processes for their preparation and pharmaceutical compositions comprising them.</p> |
