| 摘要 |
PURPOSE:To obtain testosterone-5alpha-reductase inhibitor containing a plant extract of Rosa rugosa Thunb., Saxifraga stolonifera Meerburg, Garcinia mangostana L., etc., as active ingredients and useful for androgenic alopecia, acne, prostatic hypertrophy, etc. CONSTITUTION:The objective inhibitor containing one or two or more kinds of extracts from Rosa rugosa Thunb, Saxifraga stolonifera Meerburg, Garcinia mangostana L., Nephelium lappaceum L., Pyrola japonica Klenza, Trichosanthes cucumeroides Maxim, Kadsura japonia Dunal, Cuscuta australis R. Br., Cuscuta japonica Choisy, Euchresta japonica Benth., Lilium makinoi Koidzumi and balbatimone, a wild herb as active ingredients. The extracts are extracted using water or hydrophilic organic solvent (e.g. methanol). The inhibitor can be prepared in a form of lotion, tonic, spray, solution, ointment, etc. The inhibitor is administered at a dose of 1mg to 1g/human once to several times daily in the case of treating prostatic hypertrophy and administered at a dose of 10mug to 50mg/human once to several times daily in the case of treating alopecia and acne. |
