发明名称 |
Polypeptide analogs of apolipoprotein E |
摘要 |
The present invention contemplates a method for treating hypercholesterolemia in a patient, which method comprises administering to the patient an LDL plasma concentration-reducing amount of a multimeric polypeptide capable of binding the LDL receptor. THe repeating unit of the polypeptide has an amino acid residue sequence corresponding to that represented by the formula LRKLRKRLLRDADDL.
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申请公布号 |
US5182364(A) |
申请公布日期 |
1993.01.26 |
申请号 |
US19900485158 |
申请日期 |
1990.02.26 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
DYER, CHERYL A.;CURTISS, LINDA K.;SMITH, RICHARD |
分类号 |
A61K38/00;C07K14/775;C07K16/18 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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