| 摘要 |
PCT No. PCT/EP90/01290 Sec. 371 Date Feb. 14, 1992 Sec. 102(e) Date Feb. 14, 1992 PCT Filed Aug. 7, 1990 PCT Pub. No. WO91/02510 PCT Pub. Date Mar. 7, 1991.Described are mouth and dental care preparations with improved action against the formation of plaque and containing as their active ingredients sulfophosphoric acid salts of the formula (I): <IMAGE> in which R1 and R2, independently of each other, are hydrogen, or the cation M(+) and R2 together form the group (OCnH2n)x-O-R3-SO3(-)M(+), R3 is an alkylene, hydroxyalkylene or alkenylene group with 8-22 C-atoms, n=2 or 3, x=0 or a number between 1 and 30 and M(+) is an alkali metal ion, the ammonium ion or a mono-, di- or trialkanolammonium ion with 2-4 C-atoms in the alkanol group. The preparations inhibit in vitro the dissolution and crystal growth of hydroxyapatite.
|
