发明名称 KOMPOSITION FOER FOERDROEJD OCH REGLERAD FRIGOERING OCH FOERFARANDE FOER DESS FRAMSTAELLNING
摘要 Compsn. for sustained and controlled release of a therapeutic peptide (I) is produced by (1) converting a water-soluble (I) or (I) salt into a water-insoluble (I) or salt; (2) suspending this in organic medium contg. a dissolved biodegradable polymeric material (A); (3) dispersing the suspension in aq. medium to form an oil-in-water emulsion; (4) transferring the emulsion to an excess of aq. medium and finally sepg. the resulting microspheres of (A) formed which incorporate (I).
申请公布号 SE9202213(L) 申请公布日期 1993.01.23
申请号 SE19920002213 申请日期 1992.07.21
申请人 DEBIO RECH PHARMA SA 发明人 ORSOLINI P;HEIMGARTNER F
分类号 A61K9/50;A61K9/16;A61K9/22;A61K9/26;A61K9/51;A61K9/52;A61K38/00;A61K38/04;A61K38/09;A61K38/18;A61K38/21;A61K38/22;A61K38/23;A61K38/25;A61K38/26;A61K38/28;A61K38/31;A61K38/33;A61K47/34;A61P5/06;B01J13/04;C07K7/23;(IPC1-7):A61K9/16;A61K38/08 主分类号 A61K9/50
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