KETOALKYLGLYCEROPHOSPHOLIPIDS HAVING ANTITUMOR AND ANTI-PLATELET AGGREGATION ACTIVITIES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREFROM

摘要

Compounds of general formula (I) wherein R1 is a C¿1?-C16 straight or branched alkyl group, a phenyl group or a phenyl-C6-C16alkyl group; n is an integer from 3 to 18, inclusive; R?2¿ is a C¿1?-C12 straight or branched alkyl group; R?3¿ is hydrogen, a carboxy, alkoxycarbonyl, arylalkoxycarbonyl or aryloxycarbonyl group of less than 12 carbon atoms in the last three cases; R?4, R5 and R6¿, which can be the same or different, are hydrogen, a C¿1?-C6 alkyl group or N?+R4R5R6¿ is a cyclic ammonium group, which can be aromatic or non-aromatic, wherein two of the R?4, R5 or R6¿ groups form a ring together with the nitrogen atom, and the other group is hydrogen or C¿1?-C6 alkyl, have antitumor and anti-platelet aggregating activities.