发明名称 ENTERAL USEFUL BACTERIUM-CONTAINING SUGAR-COATED TABLET
摘要 PURPOSE:To provide a sugar-coated tablet containing enteral useful bacteria, especially lactic acid bacteria, capable of allowing the bacteria to stably live in the sugar-coated tablet considered to have a bad survival environment and permitting to simultaneously use the bacteria together with other agents. CONSTITUTION:An enteral useful bacterium-containing sugar-coated tablet having the above-mentioned activities, useful in fields of drugs, foods, etc., and prepared by sugar-coating a raw tablet comprising (A) enteral useful bacteria, preferably lactic acid bacteria, especially Streptococcus.faecalis and (B) one or more stabilizers selected from polyvinylpyrrolidone, sodium carboxymethyl cellulose, sodium polyacrylate and sodium alginate. The stabilizer is compounded in an amount of 1-30wt.%, preferably 1.2-15wt.%, based on the sugar coated tablet, and can be further compounded with an intestinal disorder- preventing agent or stegnotic such as acrinol, berberine chloride or loperamide as a drug capable of being used together with the enteral useful bacteria.
申请公布号 JPH054926(A) 申请公布日期 1993.01.14
申请号 JP19910183334 申请日期 1991.06.27
申请人 DAINIPPON PHARMACEUT CO LTD 发明人 OKAMOTO SHIZUO;TANAKA TERUKAZU;MIYAMOTO KAZUO;MAKITA HIROKAZU
分类号 A61K9/28;A61K35/74;A61K47/32;A61K47/38 主分类号 A61K9/28
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