发明名称 AQUEOUS SOLUTION STABLY CONTAINING CARBAPENEM COMPOUND
摘要 PURPOSE:To obtain the subject clinically useful aqueous solution causing no decline in its potency over several hours at room temperature, excellent in stability by adjusting a specific compound within a specified range of pH values. CONSTITUTION:The objective aqueous solution containing (1R,5S,6S)-2-(6,7- dihydro-5H-pyrazolo[1,2-a] [1,2,4]-triazolium-6-yl)thio-6-[(R)--1-hydroxyethyl]-1- methyl-carbapenem-3-carboxylate of the formula, in a stably dissolved state at pH4-8 in, e.g. a 0.1M phosphoric acid buffer solution.
申请公布号 JPH051075(A) 申请公布日期 1993.01.08
申请号 JP19910178905 申请日期 1991.06.25
申请人 LEDERLE JAPAN LTD 发明人 KITAMURA MASATAKA;MATSUMOTO SHOZO
分类号 A61K31/415;A61P31/04;C07D519/00 主分类号 A61K31/415
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