摘要 |
PURPOSE:To obtain the subject clinically useful aqueous solution causing no decline in its potency over several hours at room temperature, excellent in stability by adjusting a specific compound within a specified range of pH values. CONSTITUTION:The objective aqueous solution containing (1R,5S,6S)-2-(6,7- dihydro-5H-pyrazolo[1,2-a] [1,2,4]-triazolium-6-yl)thio-6-[(R)--1-hydroxyethyl]-1- methyl-carbapenem-3-carboxylate of the formula, in a stably dissolved state at pH4-8 in, e.g. a 0.1M phosphoric acid buffer solution. |