摘要 |
PURPOSE:To enable to safely and massively produce isoamyl glycolic acid useful as a synthetic intermediate for perfume compounds from isoamyl alcohol as a raw material without metal sodium. CONSTITUTION:Isoamyl alcohol is reacted in the presence of a quaternary ammonium or a compound capable of forming the quaternary ammonium in the reaction system and a metal hydroxide salt, while removing by-produced water, and subsequently reacted with a monohalogenated acetic acid, thereby permitting to produce isoamyl glycolic acid in a high purity and in a high yield. |